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The term acne comes from a corruption of the Greek άκμή
(acne in the sense of a skin eruption) in the writings of Aëtius Amidenus.
Used by itself, the term "acne" refers to the presence of pustules and
papules. The most common form of acne is known as "acne vulgaris", meaning
"common acne". Many teenagers get this type of acne. Use of the term "acne
vulgaris" implies the presence of comedones.The term "acne rosacea" is a
synonym for rosacea, however some individuals may have almost no acne
comedones associated with their rosacea and prefer therefore the term
rosacea. Chloracne is associated with exposure to polyhalogenated
compounds.Acne develops as a result of blockages in follicles.
Hyperkeratinization and formation of a plug of keratin and sebum (a
microcomedo) is the earliest change. Enlargement of sebaceous glands and
an increase in sebum production occur with increased androgen (DHEA-S)
production at adrenarche. The microcomedo may enlarge to form an open
comedone (blackhead) or closed comedone (whitehead). Whiteheads are the
direct result of sebaceous glands becoming clogged with sebum, a naturally
occurring oil, and dead skin cells. In these conditions the naturally
occurring largely commensal bacteria Propionibacterium acnes can cause
inflammation, leading to inflammatory lesions (papules, infected pustules,
or nodules) in the dermis around the microcomedo or comedone, which
results in redness and may result in scarring or hyperpigmentation.



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